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The US president says Iranian leaders have called "to negotiate", but adds the US "may have to act" before a meeting.
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"It's like a war zone, the streets are full of blood," a source in the capital Tehran tells the BBC.
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Three teenagers and a man in his 50s died in the crash in Bolton, says Greater Manchester Police.
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Trump administration national security officials were preparing to meet on potential responses, including a range of military options.
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